This post details Microsoft’s development of a new AI tool called MAI-DxO (Microsoft AI Diagnostic Orchestrator). This AI system reportedly outperforms human doctors in diagnosing complex medical conditions. It achieves an 85% accuracy rate compared to physicians’ 20% on cases from the New England Journal of Medicine. This highlights MAI-DxO’s ability to mimic a panel of expert physicians. It has the potential to be a more cost-effective solution for diagnostics. While Microsoft acknowledges the tool is not yet ready for clinical use, the company reveals a path toward medical superintelligence. It also suggests a future with improved healthcare efficiency.
“Microsoft AI Diagnostic Orchestrator (MAI-DxO) correctly diagnoses up to 85% of NEJM case proceedings, a rate more than four times higher than a group of experienced physicians.“
Resources
Microsoft AI. (2025). The Path to Medical Superintelligence.
Time. (2025). Microsoft’s AI Is Better Than Doctors at Diagnosing Disease.

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